CD26-positive/CD326-negative circulating cancer cells as prognostic markers for colorectal cancer recurrence
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چکیده
منابع مشابه
CD26-positive/CD326-negative circulating cancer cells as prognostic markers for colorectal cancer recurrence
The present study evaluated the presence and clinical relevance of a cluster of differentiation (CD)26+/CD326- subset of circulating tumor cells (CTCs) in pre- and post-operative blood samples of colorectal cancer patients, who had undergone curative or palliative intervention, in order to find a novel prognostic factor for patient management and follow-up. In total, 80 colorectal cancer patien...
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BACKGROUND CD26, dipeptidyl peptidase IV, was discovered firstly as a membrane-associated peptidase on the surface of leukocyte. We previously demonstrated that a subpopulation of CD26+ cells were associated with the development of distant metastasis, enhanced invasiveness and chemoresistance in colorectal cancer (CRC). In order to understand the clinical impact of CD26, the expression was inve...
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ژورنال
عنوان ژورنال: Oncology Letters
سال: 2014
ISSN: 1792-1074,1792-1082
DOI: 10.3892/ol.2014.2749